Evandro M. Neto Neves, Indiana University

Dr. Neves is a Postdoctoral fellow in Emergency Medicine at Indiana University in the lab of Dr. Jeff Kline, Professor of Emergency Medicine and Physiology. His current research interests focus on the study of cardiovascular diseases, including pulmonary embolism (PE) and right ventricular dysfunction. His main hypothesis is that activated proteases, such as matrix metalloproteinases (MMPs) may contribute for the right ventricular and lung vasculature damaged following PE. Interestingly, he and his colleagues have found that doxycycline (an MMP inhibitor) attenuates PE-induced pulmonary hypertension and also protects the heart against damage (prevents troponin I release and right ventricular dilation). In addition, he believes that MMP inhibition could be a useful strategy to decrease mortality and morbidity after PE in the future. Dr. Neves is a recipient of a 2015 MCS Pappenheimer Travel Award.