Blood vessels in the microcirculation are
comprised of many different cell types, which can be identified by the
expression of various phenotypic markers. Cells in the microcirculation also
express some of the markers that cells in the nervous system express, particularly
during development or in adult remodeling. This image shows a hyaloid microvessel
in a murine eye at postnatal day three containing endothelial cells (lectin
stained in blue) and smooth muscle cells (immunostained with antibody to NG2 in
green). Some of the microvascular smooth muscle cells in the vessel are also
labeled with an antibody to beta-tubulin III (red; co-expression with NG2 makes
them appear yellow). Beta-tubulin III is a neural marker that is expressed by astrocytes
in the retina. Photo contributed and taken using a confocal
microscope (60x magnification) by Anthony Bruce in the laboratory of Dr. Shayn
Peirce-Cottler at the University of Virginia.